Two people died, seven were in critical condition and 31 others suffered injuries in a collision between two passenger trains near the western Czech town of Domazlice, Czech news agency CTK reported on Wednesday.
Czech transport Minister Karel Havlicek said on Twitter one of the trains involved was the Ex 351, which according to the Czech Railways website is a fast train from Munich to Prague.
CTK said up to 50 passengers could have been injured, citing firefighters.